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This intelligence is clearly visible, Varghese says, in the phenomenon of protein folding, the process by which proteins self-assemble from different sequences of 20 standard amino acid molecules. These proteins, which assume precise structural or functional roles in the flesh, are assembled at a rate of roughly 2,000 per second in every cell in the body (save for sex and blood cells) from thousands of these acids. The process is so complex, Varghese says, citing Scientific American, that a supercomputer programmed with the precise rules for protein folding would take billions of years to generate one final folded protein from 100 amino acids. Schroeder says chemical laws may explain the sugars, bases and phosphate components of DNA but not its rich information content.
Varghese hinges his case on other phenomena. He sites the anthropic principle, or the idea that the universe was precisely fine-tuned from the beginning for life. This "fine-tuning" is expressed in a set of physical laws and mathematical constants. If any single one of these parameters varied by the tiniest fraction, the universe as it exists would never have come into being and life would not be possible.
"Some of the 'remarkable precision' of physical parameters that people talk about is highly misleading because it depends on the choice of units," counters Victor Stenger in God. The flaw in the principle, he says, is that a single parameter is varied while the others remain fixed. But what if you varied each parameter in concert? Stenger says it's plausible to construct a cosmology in which stars, planets and intelligent life arise with different sets of parameters varying from those currently observed.
But perhaps the most confounding puzzle undermining the theory that life and intelligence is fully explainable in material terms is the origin of reproduction. "How did reproduction start?" asks Varghese. "Nobody dares discuss that."
This is where evolutionary materialism backs itself into a wall. Reproduction is the engine driving the whole evolutionary process. "How is it that the first living beings had the power of replication?" he writes. "How is it that life came with this fundamentally purposive capability preinstalled?" Darwin himself admitted in Origin of Species his whole theory rests on the existence of an unexplained being already in possession of reproductive powers "into which life was first breathed."
Scientists admit reproduction is baffling, and they offer a variety of speculative explanations. "It was originally just an accident," says Keith Parsons. Precursors to reproduction are inherent throughout the natural world, he says, citing complex molecules forming other compounds that multiply in chain reactions.
Stenger points out that computer and mathematical models have been composed employing very simple rules from which complex patterns emerge and then reproduce themselves, though he admits such models are just an analogy and still require intelligence to create the programs. Ruben says the puzzle of reproduction may be unraveled through study of self-replicating forms of RNA, the compound that functions in protein synthesis and carries protein codes from the cell's nucleus to sites where proteins are formed. "You can replicate RNA in a test tube," he says. "Making it [self-]replicate, that's the holy grail right now." He has no doubt that the riddle will be solved. "Science can't suddenly say, 'God did this and it happened,'" he says. "You could replace God with aliens. You could replace God with anything else."
Yet it's Flew's rejection of atheism that triggered the ruckus. Varghese's film is interspersed with clips from a debate at the University of North Texas in 1976 between Flew and theologian Thomas B. Warren. Flew's arguments erupt like bullets propelled by bursts of condescension.
"Certainly I am inclined to believe the universe is without beginning, and will be without end," he says. Belief in God is a self-contradiction, Flew insists. Belief in God as all-powerful and all-good is inconsistent with the undenied evils in the world and with the system of salvation and damnation He created. "If after all the things that are said about his proposed being are contradictory, then to say that there is such a being, thus and thus described, is like saying there is a round square or an unmarried husband," he scoffs.