David Cronenberg is a master of simplicity. The Fly (1986) is a remake of a 1958 film of the same name that's a bit more plot-heavy. There are flashbacks, I mean. Cronenberg took the '58 film and cut the fat, and made it about his very favorite subject -- the relationship of the mind and the body.
In this case, it's about complete transformation physically (into a weirdly moist-skinned fly), while the mind retains it's Jeff Goldblum-y psychology. Somehow, he keeps it simple and terrifying. The Fly (1958) is a good rent, for sure, but stick with Cronenberg for some primal terror. Few filmmakers are better at making your skin crawl.
The most memorable scene after the jump...
Most Memorable Scene:
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Oh Jesus, the fingernail sequence. Jesus. Jesus. If you've seen it--you know what I'm talking about. Cringing ... summarizing: Jeff Goldblum, after his DNA merges with a fly, starts to transform. He goes into the bathroom, bites his fingernail, and it comes loose (AHHH! AHHH!). Then, he peels another off. And. And. When he presses his finger, a WEIRD JUICE SPITS OUT. OK, I'm done.